Endocrine Abstracts

Ubiquitin (Ub) plays a critical role in many fundamental processes like cell cycle, apoptosis, DNA repair or endocytosis. In these processes Ub acts as a signalling component able to trigger molecular events in cells. Ub does so by operating as a reversible and highly versatile regulatory signal for an expanding number of Ub-binding domains (UBD) present in cellular proteins that convey Ub signals into appropriate cellular phenotypes. In addition, it is becoming apparent that ...